
Sederma - essential in cosmetic actives
With almost 60 years of experience in the field, Sederma is a cosmetic ingredient specialist in constant research of innovative concept and ingredients with proven efficacy. Sederma has developed a unique range of more than 140 bioactive ingredients, with substantiated efficacy for skin care (anti-ageing, moisturising, sebum control, etc.) as well as hair care, colour cosmetics and body care. Sederma's teams are constantly innovating in biotechnology, molecular synthesis, vegetal extraction and plant cell culture.
With a strong certification policy ,Sederma strives for continuous improvement of quality, safety, sustainability, ethics and has received the following certifications:ISO 14001, ISO 45001, ISO 9001, AEO, Cosmetic Ingredient Good Manufacturing Practice (EFfCI), RSPO and Halal. Sederma has also been evaluated by Sedex™ and Ecovadis™ (score 83/100 - Gold status) and is an UEBT member since 2020.
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Matrixyl® Range
WORLWIDE KNOWN ANTI-AGEING AND ANTI-WRINKLE ACTIVE INGREDIENTSDiscover our worldwide known Matrixyl® range. Its name being synonymous with efficacy and reliability in fighting ageing signs.
Discover the Matrixyl® rangePlant biotechnology in cosmetics
Plant biotechnology in cosmetics: Sederma has chosen to develop plant biotechnology to produce molecules of interest in quantities without causing any damage to the environment. Discover our plant biotechnology range with guaranteed efficacy, reproducibility and absolute sustainability
Learn moreMicrobial biotechnology in cosmetics
Microbial biotechnology in cosmetics Page Summary SubtitleMicrobial biotechnology in cosmetics: Sederma has chosen to develop microbial biotechnology to produce molecules of interest in quantities without causing any damage to the environment. Discover our range issued from microbial biotechnology with guaranteed efficacy, reproducibility and absolute sustainability.
Learn moreOur on trend Sederma active ingredients
With an ageing population around the globe, the demand for anti-ageing skin care products is not decreasing. However, the aim is no longer to fight against age, but to beautify the skin, while feeling good about the ageing phenomenon. Anti-ageing products have shifted to pro-ageing products. Wrinkles prevent, moisturising, seboregulating, firming, radiance, ... there are specific products for every skin type, all age groups, lifestyles and budgets.
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Mel[o]stem™
Mel[o]stem™ is dedicated to fading both age and sun exposure pigmentation disorders (dark and flat white spots) for an even skin complexion. This smart adaptive ingredient, obtained from plant cell...

Matrixyl® 3000
Matrikines anti-wrinkle complex helps reverse the chronological ageing as attested by the regulation of senescence markers and reduce the cutaneous photo damage by restructuring the fragile network of...

ReVitAlide™
Encapsulated retinol by Sederma. ReVitAlide™ provides enhanced stability of retinol easing its formulation. It also improves retinol bioavailability into the skin reinforcing its efficacy.
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Ameyezing™
Dedicated to improving the appearance of both hyperpigmented and vascular dark circles.

Feminage™
Fights against skin sagging. Feminage™ offers skin elasticity and firming benefits, helping reduce jowl sagging, droopy eyelids, crow’s feet wrinkles and marionette lines of menopausal women.

Ceramide A2™ PH
Reinforces hair sheath; protects and repairs hair from chemical aggressions

Kombuchka™ PH
Improvement in skin quality (smoothing, radiance), anti-glycation, lipofilling effect

Synchrolife™
Realigning circadian rhythms, counteracting the effects of digital pollution, erasing signs of fatigue, delivering neuro-beauty benefits with a stronger self-esteem and an overall well-being,… These...

PoreTect®
PoreTect® is the new skin texture rejuvenator from Sederma. Acting as a skin architect, this eco-designed active ingredient counteracts the age-related cutaneous pore enlargement phenomenon....

OptimHyal®
OptimHyal® is a new skin smoothing active ingredients obtained by biofermentation. OptimHyal® contains Glycokines™ which stimulate hyaluronic acid neosynthesis and sustain its turnover.

Legance®
Designed to provide a global anti-ageing benefit to the legs, Legance® has proved its efficiency to improve the appearance and comfort of the legs by reducing water retention and refining the adipose...
Restorating the original hair pigmentation, repairing damaged hair, protecting it from pollution, lessening hair loss, reducing dandruff condition, and soothing scalp itching, here are some of the benefits that our range of hair and scalp care active ingredients can bring to your product development. Discover them below!

Silverfree™
This biomimetic peptide supports the progressive restoration of the original hair pigmentation with a remnant effect, while protecting it from oxidative damage.
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Hairspa™
Hairspa™ helps to control the development of pathogens while potentiating and preserving the activity of local probiotics.

Fruitbio
Smoothes the hair cuticles

Apiscalp®
Apiscalp® has been designed to provide beauty and comfort to both oily scalp and dry scalp. Apiscalp® fights against dandruff, itching, dryness and hyperseborrhea. From a natural origin, Apiscalp®...
Discover our active ingredients to protect and prevent against screen exposure damage and answer the needs of the more connected consumers.

Synchrolife™
Realigning circadian rhythms, counteracting the effects of digital pollution, erasing signs of fatigue, delivering neuro-beauty benefits with a stronger self-esteem and an overall well-being,… These...

Citystem®
This eco-designed active ingredient provides a global solution against both environmental and screen light pollution damage to the skin to leave it looking smooth and flawless. A recent test showed...

Amberstem®
This eco-designed active ingredient evens the skin tone and fades dark areas. Amberstem® provides a lucent and healthy amber tone to olive complexions.
Spotlight on eyes! As face coverings direct a focus on the upper half of the face, give the eye area more attention. Dark circles, under-eye puffiness, sagging upper eyelids and crow's feet are common eye contour imperfections that can alter the beauty of the face. Get rid of these thanks to our ingredients!
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Ameyezing™
Dedicated to improving the appearance of both hyperpigmented and vascular dark circles.

Haloxyl®
Fights against the accumulation of blood degradation products around the eyes
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Eyeliss™
Reduces bags and puffiness under the eyes
The innovation stands on the additional benefits colour cosmetic products can offer behind their decorative purpose. Find out the perfect claim to add to your colour cosmetic products thanks to our active ingredients.

Neonyca®
Neonyca® helps improving nail thickness, smoothness, cohesion and moisture. It provides beauty and resilience to the nail while enhancing the beauty properties of nail polish. This natural ingredient...

Majestem® Drypure®
This powder version of Majestem® is an eco-designed, pure lyophilised plant cell culture extract, without excipient, easily dispersible in powder make-up or powder format skincare. Effective right...

Volulip™
Lip plumper and anti-ageing by hyaluronic acid synthesis
Skin microbiota has been widely discussed in the cosmetics industry over the past couple of years. With the increase in hand washing and sanitising due to the COVID crisis, keeping the skin microbiota in a healthy balance has become a critical personal care issue globally which is set to continue as we enter our ‘new normal’. Specific to each individual, our microbiotic ecosystem is an essential ally to our beauty assets and well-being. Find out more about how Sederma active ingredients help rebalance the skin microbiota.
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BB-Biont™
BB-BIONT™ is a biomimetic peptide and a gentle alternative to aesthetic medicine allowing to smooth the appearance of pockmarks.
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Ecodermine™
Ecodermine™ helps to control the development of pathogens while potentiating and preserving the activity of local probiotics.
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Hairspa™
Hairspa™ helps to control the development of pathogens while potentiating and preserving the activity of local probiotics.
Body care is one of the most dynamic cosmetic markets thanks to the emergence of new trends like the 'Active Beauty' and the 'Spa-at-Home'. Find below a selection of our active ingredients for your body care product range
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BB-Biont™
BB-BIONT™ is a biomimetic peptide and a gentle alternative to aesthetic medicine allowing to smooth the appearance of pockmarks.
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Ecodermine™
Ecodermine™ helps to control the development of pathogens while potentiating and preserving the activity of local probiotics.

Intenslim®
Natural fat burner. Fights fat accumulation, particularly on the stomach area, promotes the synthesis of desnutrin, a key enzyme in lipolysis activation, soothes the inflammation reaction caused by...

Legance®
Designed to provide a global anti-ageing benefit to the legs, Legance® has proved its efficiency to improve the appearance and comfort of the legs by reducing water retention and refining the adipose...
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Explore Sederma rangeActive ingredients recent blog posts

The Timeless Greatness of Rose in Natural Cosmetics
Discover the beauty secrets to skincare brought by roses through the millennia and on to modern cosmetics!
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Phytessence™ French Rose EC
Unveil the skin's natural beauty with Crodarom's latest extract! Eco-designed to provide the hydrating, protecting and soothing properties of locally sourced organic rose flowers!
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Geoskincare takes centre stage in beauty trends for 2024
Dive into the new beauty concept that acknowledges that skin's needs differ based on geographical regions – from temperate to extreme climates!
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Portfolio expansion: Tech & Nature combine for biotech success
Learn more about our range of biotechnology-derived, bio-based ceramides, sphingolipids and phospholipids, and the powerful benefits they can deliver to your cosmetic formulations.
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Be ACTIVEly Committed

Skin brightening in Asia
Skin brightening is still a strong claim in cosmetics. Explore this market trend and evolutions as well as Sederma’s active ingredients and examples of trending formulas to fit your customer needs.