
Sederma - essential in cosmetic actives
Discover Sederma
Constantly looking for proven efficacy
Sederma has been a cosmetic active ingredient specialist for more than 50 years and it is in constant research of proven efficacy.
Equipped with a high performance and modern claim substantiation laboratory, Sederma carries out powerful in vitro, ex vivo and in vivo tests to prove the efficacy of its products.
Innovation through concepts and ingredients
Sederma's teams are constantly innovating in biotechnology, molecular synthesis, vegetal extraction and plant cell culture.
The R&D department work in synergy with the sales and marketing team, as well as the regulatory service to create innovative concept and ingredients.
R&D and manufacturing to administration and warehousing, are gathered in a 11 000 m² complex located in Le Perray-en-Yvelines (France).
Be ACTIVEly Committed
At Sederma, we are ACTIVEly Committed to minimise our social and environmental impacts on our stakeholders without compromising innovation, quality and safety in line with Croda's purpose "Smart science to improve lives™". The strategy is built with the aim of sustainability innovating a policy of continuous improvement and to set-up a holistic view of doing business by placing equal emphasis on the Planet, People and Profit. As a result, we can ensure consistency between our product portfolio and our internal CSR policy management.
Quality and Reliability
Modern and sophisticated equipement to allow strong production capabilities and reliability.
We have a strong certification policy and Sederma strives for continuous improvement of quality, safety, sustainability, ethics and has received the following certifications: ISO 14001, ISO 45001, ISO 9001, AEO, Cosmetic Ingredient Good Manufacturing Practice (EFfCI), RSPO and Halal. Sederma has also been evaluated by Sedex™ and Ecovadis™ (score 83/100 - Gold status).
Reliability and recognitions:
- We developed and still produce Matrixyl®, one of the best-known anti-ageing active ingredients.
- More than 140 cosmetic active ingredients on the market
- 81 patent families for both active ingredients and technology
- 17 awards worldwide
Product Finder
Our on trend Sederma active ingredients
With an ageing population around the globe, the demand for anti-ageing skin care products is not decreasing. However, the aim is no longer to fight against age, but to beautify the skin, while feeling good about the ageing phenomenon. Anti-ageing products have shifted to pro-ageing products. Wrinkles prevent, moisturising, seboregulating, firming, radiance, ... there are specific products for every skin type, all age groups, lifestyles and budgets.

ReVitAlide™
Encapsulated retinol by Sederma. ReVitAlide™ provides enhanced stability of retinol easing its formulation. It also improves retinol bioavailability into the skin reinforcing its efficacy.
.png&mn=personalcare&w=768&xr=0&yr=0&xfp=6&yfp=6&hash=EED602919C1E1AAB2C613358C8E766B719C138999FEC74AA)
Ameyezing™
Dedicated to improving the appearance of both hyperpigmented and vascular dark circles.

Feminage™
Fights against skin sagging. Feminage™ offers skin elasticity and firming benefits, helping reduce jowl sagging, droopy eyelids, crow’s feet wrinkles and marionette lines of menopausal women.

Ceramide A2™ PH
Reinforces hair sheath; protects and repairs hair from chemical aggressions

Kombuchka™ PH
Improvement in skin quality (smoothing, radiance), anti-glycation, lipofilling effect

Synchrolife™
Realigning circadian rhythms, counteracting the effects of digital pollution, erasing signs of fatigue, delivering neuro-beauty benefits with a stronger self-esteem and an overall well-being,… These...

PoreTect®
PoreTect® is the new skin texture rejuvenator from Sederma. Acting as a skin architect, this eco-designed active ingredient counteracts the age-related cutaneous pore enlargement phenomenon....

OptimHyal®
OptimHyal® is a new skin smoothing active ingredients obtained by biofermentation. OptimHyal® contains Glycokines™ which stimulate hyaluronic acid neosynthesis and sustain its turnover.

Legance®
Designed to provide a global anti-ageing benefit to the legs, Legance® has proved its efficiency to improve the appearance and comfort of the legs by reducing water retention and refining the adipose...
Restorating the original hair pigmentation, repairing damaged hair, protecting it from pollution, lessening hair loss, reducing dandruff condition, and soothing scalp itching, here are some of the benefits that our range of hair and scalp care active ingredients can bring to your product development. Discover them below!

Silverfree™
This biomimetic peptide supports the progressive restoration of the original hair pigmentation with a remnant effect, while protecting it from oxidative damage.
.jpg&mn=personalcare&w=768&xr=0&yr=0&xfp=6&yfp=6&hash=A11B8228881BCC31AF5437C1484B055219C138999FEC74AA)
Hairspa™
Hairspa™ helps to control the development of pathogens while potentiating and preserving the activity of local probiotics.

Fruitbio
Smoothes the hair cuticles

Apiscalp®
Apiscalp® has been designed to provide beauty and comfort to both oily scalp and dry scalp. Apiscalp® fights against dandruff, itching, dryness and hyperseborrhea. From a natural origin, Apiscalp®...
Discover our active ingredients to protect and prevent against screen exposure damage and answer the needs of the more connected consumers.

Synchrolife™
Realigning circadian rhythms, counteracting the effects of digital pollution, erasing signs of fatigue, delivering neuro-beauty benefits with a stronger self-esteem and an overall well-being,… These...

Amberstem®
This eco-designed active ingredient evens the skin tone and fades dark areas. Amberstem® provides a lucent and healthy amber tone to olive complexions.
Spotlight on eyes! As face coverings direct a focus on the upper half of the face, give the eye area more attention. Dark circles, under-eye puffiness, sagging upper eyelids and crow's feet are common eye contour imperfections that can alter the beauty of the face. Get rid of these thanks to our ingredients!
.png&mn=personalcare&w=768&xr=0&yr=0&xfp=6&yfp=6&hash=EED602919C1E1AAB2C613358C8E766B719C138999FEC74AA)
Ameyezing™
Dedicated to improving the appearance of both hyperpigmented and vascular dark circles.

Haloxyl®
Fights against the accumulation of blood degradation products around the eyes
.jpg&mn=personalcare&w=768&xr=0&yr=0&xfp=6&yfp=6&hash=159F8322726234D105BBD5EFB4EBE55519C138999FEC74AA)
Eyeliss™
Reduces bags and puffiness under the eyes
The innovation stands on the additional benefits colour cosmetic products can offer behind their decorative purpose. Find out the perfect claim to add to your colour cosmetic products thanks to our active ingredients.

Neonyca®
Neonyca® helps improving nail thickness, smoothness, cohesion and moisture. It provides beauty and resilience to the nail while enhancing the beauty properties of nail polish. This natural ingredient...

Majestem® Drypure®
This powder version of Majestem® is an eco-designed, pure lyophilised plant cell culture extract, without excipient, easily dispersible in powder make-up or powder format skincare. Effective right...

Volulip™
Lip plumper and anti-ageing by hyaluronic acid synthesis
Skin microbiota has been widely discussed in the cosmetics industry over the past couple of years. With the increase in hand washing and sanitising due to the COVID crisis, keeping the skin microbiota in a healthy balance has become a critical personal care issue globally which is set to continue as we enter our ‘new normal’. Specific to each individual, our microbiotic ecosystem is an essential ally to our beauty assets and well-being. Find out more about how Sederma active ingredients help rebalance the skin microbiota.
.jpg&mn=personalcare&w=768&xr=0&yr=0&xfp=6&yfp=6&hash=52F7E12C58BA54ADFCF156A322CA0BA919C138999FEC74AA)
BB-Biont™
BB-BIONT™ is a biomimetic peptide and a gentle alternative to aesthetic medicine allowing to smooth the appearance of pockmarks.
.jpg&mn=personalcare&w=768&xr=0&yr=0&xfp=6&yfp=6&hash=A525A902E5AFAAEA49E680944E66746119C138999FEC74AA)
Ecodermine™
Ecodermine™ helps to control the development of pathogens while potentiating and preserving the activity of local probiotics.
.jpg&mn=personalcare&w=768&xr=0&yr=0&xfp=6&yfp=6&hash=A11B8228881BCC31AF5437C1484B055219C138999FEC74AA)
Hairspa™
Hairspa™ helps to control the development of pathogens while potentiating and preserving the activity of local probiotics.
Body care is one of the most dynamic cosmetic markets thanks to the emergence of new trends like the 'Active Beauty' and the 'Spa-at-Home'. Find below a selection of our active ingredients for your body care product range
.jpg&mn=personalcare&w=768&xr=0&yr=0&xfp=6&yfp=6&hash=52F7E12C58BA54ADFCF156A322CA0BA919C138999FEC74AA)
BB-Biont™
BB-BIONT™ is a biomimetic peptide and a gentle alternative to aesthetic medicine allowing to smooth the appearance of pockmarks.
.jpg&mn=personalcare&w=768&xr=0&yr=0&xfp=6&yfp=6&hash=A525A902E5AFAAEA49E680944E66746119C138999FEC74AA)
Ecodermine™
Ecodermine™ helps to control the development of pathogens while potentiating and preserving the activity of local probiotics.

Intenslim®
Natural fat burner. Fights fat accumulation, particularly on the stomach area, promotes the synthesis of desnutrin, a key enzyme in lipolysis activation, soothes the inflammation reaction caused by...

Legance®
Designed to provide a global anti-ageing benefit to the legs, Legance® has proved its efficiency to improve the appearance and comfort of the legs by reducing water retention and refining the adipose...
Active ingredients recent blog posts

Synthetic biology in cosmetics: limitless perspectives
Have you already heard about synthetic biology? Learn about synthetic biology and numerous sustainable benefits to produce molecules of interest for cosmetic applications.
Read more
Body Positive Movement: The role of natural cosmetics
The Body Positive social movement has led the major developments in the body care market in the recent years, with the skinification and healthification of cosmetics. Discover how high-performance...
Read more
Retinol vs Encapsulated retinol: Encapsulation technologies for more effective cosmetic actives.
What is retinol? How does it work in the skin? What retinol issues does ReVitAlide™, the Sederma’s encapsulated retinol solve? This blog gives you the answers to these questions.
Read more
Beauty Trends 2023 : new concepts for successful personal care products
Let’s discover in this blog article the new beauty trends for 2023 and get inspired by new concepts and consumer insights presented by Crodarom and Alban Muller.
Read more
Matrixyl® Range
WORLWIDE KNOWN ANTI-AGEING AND ANTI-WRINKLE ACTIVE INGREDIENTSDiscover our worldwide known Matrixyl® range. Its name being synonymous with efficacy and reliability in fighting ageing signs.
Discover the Matrixyl® rangePlant biotechnology in cosmetics
Plant biotechnology in cosmetics: Sederma has chosen to develop plant biotechnology to produce molecules of interest in quantities without causing any damage to the environment. Discover our plant biotechnology range with guaranteed efficacy, reproducibility and absolute sustainability
Learn moreMicrobial biotechnology in cosmetics
Biotechnology Page Summary SubtitleMicrobial biotechnology in cosmetics: Sederma has chosen to develop microbial biotechnology to produce molecules of interest in quantities without causing any damage to the environment. Discover our range issued from microbial biotechnology with guaranteed efficacy, reproducibility and absolute sustainability.
Learn more
Be ACTIVEly Committed

ReVitAlide™
Latest product launch: discover Revitalide™, the Sederma’s hero encapsulated retinol that answers the market demand for stable, easy-to-formulate, highly boiavailable and well-tolerated retinol.

Inspiring Formulations for the Asian Market
Discover our new kit of formulations named Inspiring formulations for the Asian market. These formulations are focus on "perfect skin" achievement, suitable for the physiological of Asian skin and they help to fix skin issues caused by the pandemic.