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Personal Care

Mel[o]stem™

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Mel[o]stem™ is dedicated to fading both age and sun exposure pigmentation disorders (dark and flat white spots) for an even skin complexion. This smart adaptive ingredient, obtained from plant cell culture, also offers unique sustainable attributes and full transparency on its sourcing and processing.

INCI name

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Melostem
Fading dark spots with Melostem: visualise the results TO Fading dark spots with Melostem: visualise the results T2
Visualise the results

Fading dark spots with Mel[o]stem™: Use the slider to see the effect, simulation for illustration only.


Maximum pigmentation

2.3x less intense vs placebo**

(down to -19 %*/T0)

 

Pigmentation heterogeneity

3.8x more homogeneous vs placebo**

(down to -32 %*/T0)

An expert-meseaured 64% improvement of complexion evenness vs placebo.

Picture analysis, pigmentation measurement by Antera 3D® camera.

Significance: * p<0.01, ** p<0.05

 

Toning down white spots with Mel[o]stem™: visualise the results T0 Toning down white spots with Mel[o]stem™: visualise the results T2
Visualise the results

Toning down white spots with Mel[o]stem™: Use the slider to see the effect, simulation for illustration only.

 

Lesion volume

2.7x smaller vs placebo**
(down to -93 %*/T0)

Maximum depth

2.4x less deep vs placebo**
(down to -47 %*/T0)

Mel[o]stem™ significantly reduces the appearance of white spots on the skin.

Significance: * p<0.01, ** p<0.05

 

Product details

Physical form at 25°C

  • Liquid

Chemistry

  • Plant cell culture

Functions

  • Active ingredients

Regional availability

  • Asia
  • Europe
  • Latin America
  • N America

Applications

  • After sun
  • Face / neck skin care
  • Sun protection

Consumer benefit

  • Ageing
  • Brightening / age spots

Certifications and standards

  • RSPO
  • ISO 16128 - derived natural
  • Vegan suitable

Ingredient origin

  • Plant derived

Composition information

  • EO/PO free
  • Preservative free
  • EDTA free
  • BHT / BHA free
  • Sustainable palm (RSPO MBAL)

% Natural origin content – ISO 16128

  • 100

Manufacturing processes

  • Plant cell culture

Biodegradability

  • Readily biodegradable

Mel[o]stem™, watch the video presentation

Discover Mel[o]stem™, Sederma’s smart adaptive active ingredient which fades both sun related dark and white spots and cocoons melanocytes, the cutaneous cells which ensure skin’s sun capital.   

Formulations

Décolleté day cream

Multi-benefit cream provides both a perfect skin care for a harmonious younger skin thanks to Matrixyl® MBAL and an excellent complexion unifying base thanks to Mel[o]stem™. Mel[o]stem™ improves complexion uniformity while Matrixyl® MBAL visibly reduces wrinkles. Solaveil™ XT-300 MBAL brings a low...

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Say goodbye to age-spots cream

This light and non-greasy emulsion, with excellent skin tolerance, was used in the clinical in vivo study validating the in vitro data and demonstrating the efficacy of Mel[o]stem™ in reducing both dark and white age-spots.

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Blemish jelly eraser

Recover an even and radiant complexion thanks to this blemish jelly eraser. Mel[o]stem™ improves complexion while BB-Biont™ MBAL acts on skin’s texture, fading away acne marks. Syncrowax™ ERLC and Syncrowax™ HRC in association with SP Cithrol™ GMS SE 40 MBAL build the architecture of the jelly...

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Honey glow custard

This honey glow custard is the ideal day starter skin care. It contains Mel[o]stem™, a natural youth therapy that unifies complexion, while Crystalide™MBAL, a bio-harmonical peptide, works as a natural highlighter making the skin feels smooth, clear and glowy. The special combination of Amigum and...

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2 in 1 stop thirst and age-spots face mist

Melostem™ MBAL evens out complexion while Revidrate™ MBAL acts on the active layer of the epidermis, promoting skin’s natural moisturising components for a perfectly constructed barrier. Phytolea™ Pomegranate is a natural moisturising and nourishing oil perfectly suited for mature skin formulations....

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Pampering fresh balm

This creamy O/W textured balm with Mel[o]stem™ and Juvinity™ MBAL is the perfect formulation to pamper your skin. Mel[o]stem™ improves complexion uniformity; Juvinity™ MBAL. smoothes wrinkles, restructures, and densifies the dermis. To achieve this fresh and rich balm texture, the emulsifier SP...

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